The thiolato-bridged binuclear molybdenum complexes [Mo2CP2L2(mu-SMe)(2)(mu-L’)]Y (Cp = eta(5)-C5H5; L’ = SMe, L = Bu’NC (1a), xylNC (1b) or CO (3); L’ = PPh2, L = Bu’NC (16); Y = …more
OBJECTIVES: With combined positron emission tomography and computed tomography (CT), we investigated coronary arterial uptake of 18F-sodium fluoride (18F-NaF) and 18F-fluorodeoxyglucose (18F-FDG) as markers of active plaque calcification and inflammation, …more
BACKGROUND: Coronary artery calcification is pathognomonic of coronary artery disease (CAD). Whether CAD in patients with COPD is linked to lung function, functional capacity and/or clinically relevant outcomes is unknown. …more
Background: A blood test that quantified the extent of brain damage following ischaemic stroke might be a useful surrogate outcome measure in trials of acute stroke treatments. Measures of neuronal …more
The variability in clinical features and the masking effects of drug therapy in Parkinson’s disease (PD) can affect clinical assessment of disease severity. The aim of this study was to …more
BACKGROUND: It has been proposed that different types of psychopathology in schizophrenia may reflect distinguishable pathological processes. In the current study we aimed to address such associations in the absence …more
Imitation is thought to require a perception-action matching process that utilizes the “mirror neuron” system, but other cognitive functions such as error detection may also be required for even simple …more
Background: Schizophrenia is associated with cortical thickness reductions in the brain, but it is unclear whether these are present before illness onset, and to what extent they are driven by …more
Quinuclidinyl benzilate (QNB) and its derivatives are being developed to investigate muscarinic receptor changes in vivo in Alzheimer’s disease and dementia with Lewy bodies. This is the first study of …more