Collaborations help to stimulate scientific research by sharing of expertise, knowledge, equipment, and research products. Cooperation benefits multicentre positron emission tomography (PET) trials by speeding up recruitment, allowing larger studies …more
Perfluoroalkyl-substituted, enantiopure C-2-symmetric N and N,O ligands showing affinity either for standard organic solvents or perfluorocarbons have been conveniently prepared from readily available precursors. Preformed cobalt(II) and in-situ-generated copper(I) complexes …more
cAMP is a key mediator of a number of molecules that induce growth cone chemotaxis, including netrin-1 and myelin-associated glycoprotein (MAG). Endogenous neuronal cAMP levels decline during development, and concomitantly …more
PURPOSE: To perform a systematic review to determine the accuracy of computed tomographic (CT) angiography, magnetic resonance (MR) angiography, and transcranial Doppler ultrasonography (US) in depicting intracranial aneurysms. MATERIALS AND …more
Background and Purpose – Early ischemic changes on noncontrast CT in acute stroke include both hypoattenuation and brain swelling, which may have different pathophysiological significance. Methods – Noncontrast CT and …more
It has long been suspected that cortical interhemispheric asymmetries may underlie hemispheric language dominance (HLD). To test this hypothesis, we determined interhemispheric asymmetries using stereology and MRI of three cortical …more
The reaction of the perfluorosulfanylvinyldiiron(I) complex [{Fe(CO)(3)}(2){mu-C(SMe)(CF3)C-beta(CalphaF2)}] (1) with secondary mono- and diamines (L = Me2NH, (CH2)(4)NH, HN(CH2)(4)NH) in a 1:1 ratio in dichloromethane at room temperature led in a …more
Cardiac CT is a rapidly advancing technology. Non-invasive CT coronary angiography is an established technique for assessing coronary heart disease with accuracy similar to invasive coronary angiography. CT myocardial perfusion …more
Blood-brain barrier (BBB) dysfunction may contribute to the risk of Alzheimer’s disease (AD). Dynamic contrast-enhanced magnetic resonance imaging (MRI) was performed repeatedly nine times before and up to 30 min …more
BACKGROUND AND PURPOSE: Increased blood-brain barrier (BBB) permeability occurs in cerebral small vessel disease. It is not known if BBB changes predate progression of small vessel disease. METHODS: We followed-up …more
Cerebral “microvascular” disease occurs in lacunar stroke, leukoaraiosis, vascular dementia and Alzheimer’s disease. It may arise from or contribute to insidious damage to the blood-brain barrier (BBB). We systematically reviewed …more