Author(s)
T. K. Hutton, K. W. Muir, D. J. Procter
ISBN
1523-7060
Publication year
2003
Periodical
Organic Letters
Periodical Number
25
Volume
5
Pages
4811-4814
Author Address
[GRAPHICS] gamma,delta-Unsaturated ketones undergo two very different stereoselective cyclization reactions mediated by samarium(II) iodide depending upon the alcohol cosolvent used in the reaction. Switching between an unprecedented aldol spirocyclization and a novel cyclobutanol-forming process can be achieved simply by changing the alcohol cosolvent from methanol to tert-butyl alcohol.