Upcoming Events

PET is Wonderful Annual Meeting 2018 Oct 29, 2018 09:00 AM - 05:00 PM — South Hall Complex, Pollock Halls, University of Edinburgh
2018 NHS Research Scotland Annual Conference Oct 30, 2018 09:00 AM - 05:00 PM — Perth Concert Hall
8th SINAPSE Neuro-oncology Meeting Oct 30, 2018 09:30 AM - 04:00 PM — Royal College of Physicians and Surgeons of Glasgow, 232-242 St Vincent Street, Glasgow
Image Guided Therapies Network+ Tri-Annual Meeting Nov 01, 2018 10:00 AM - 05:00 PM — Wolfson Lecture Theatre, Ninewells Hospital, Dundee
7th Annual Scottish Radiotherapy Research Forum Nov 01, 2018 10:00 AM - 04:30 PM — Stirling Court Hotel, University of Stirling

SINAPSE Image of the Month: Liver T1 mapping

October 2017 SINAPSE Image of the Month

Courtesy of Dr Jonathan Fallowfield, this image shows LiverMultiscan MRI axial T1 relaxation maps of liver in the same patient before [left] and 4 weeks after [right] treatment of portal hypertension with non-selective beta-blockers (NSBBs). Top row shows representative image of liver T1 relaxation map from a single patient; position of 3 regions of interest is indicated by white circles. Bottom row shows corresponding segmented liver histograms and T1 colour scales. Numbers below each histogram represent the mode T1.

Non-invasive biomarkers are urgently needed for diagnosis, monitoring and evaluating treatment response in patients with portal hypertension (a condition which underlies most of the lethal complications of liver cirrhosis such as variceal bleeding). The image is taken from a recent study published in BioMed Research International, reporting the first use of quantitative MRI markers (phase-contrast MR angiography and T1 mapping) for the haemodynamic assessment of NSBBs in portal hypertension in a small randomized feasibility study:

McDonald N, Lilburn DML, Lachlan NJ, Macnaught G, Patel D, Jayaswal ANA, Hayes PC, Semple SI, Fallowfield JA. Assessment of Haemodynamic Response to Nonselective Beta-Blockers in Portal Hypertension by Phase-Contrast Magnetic Resonance Angiography. BioMed Research International, 2017, 9281450.