Upcoming Events

2nd SINAPSE Image Analysis meeting Jun 20, 2019 09:00 AM - 05:30 PM — Lecture Theatre 2, Dalhousie Building, University of Dundee
2019 SINAPSE ASM Jun 21, 2019 09:30 AM - 05:00 PM — Apex City Quay Hotel, Dundee
2nd International Conference on Medical Imaging with Deep Learning Jul 08, 2019 - Jul 10, 2019 — ICL South Kensington Campus, London
4th International Workshop on Image Processing Techniques and Applications Jul 22, 2019 - Jul 23, 2019 — Centre for Mathematical Imaging Techniques (CMIT), University of Liverpool, England
Medical Image Understanding and Analysis Conference 2019 Jul 24, 2019 - Jul 26, 2019 — University of Liverpool, England

SINAPSE Image of the Month: Liver T1 mapping

October 2017 SINAPSE Image of the Month

Courtesy of Dr Jonathan Fallowfield, this image shows LiverMultiscan MRI axial T1 relaxation maps of liver in the same patient before [left] and 4 weeks after [right] treatment of portal hypertension with non-selective beta-blockers (NSBBs). Top row shows representative image of liver T1 relaxation map from a single patient; position of 3 regions of interest is indicated by white circles. Bottom row shows corresponding segmented liver histograms and T1 colour scales. Numbers below each histogram represent the mode T1.

Non-invasive biomarkers are urgently needed for diagnosis, monitoring and evaluating treatment response in patients with portal hypertension (a condition which underlies most of the lethal complications of liver cirrhosis such as variceal bleeding). The image is taken from a recent study published in BioMed Research International, reporting the first use of quantitative MRI markers (phase-contrast MR angiography and T1 mapping) for the haemodynamic assessment of NSBBs in portal hypertension in a small randomized feasibility study:

McDonald N, Lilburn DML, Lachlan NJ, Macnaught G, Patel D, Jayaswal ANA, Hayes PC, Semple SI, Fallowfield JA. Assessment of Haemodynamic Response to Nonselective Beta-Blockers in Portal Hypertension by Phase-Contrast Magnetic Resonance Angiography. BioMed Research International, 2017, 9281450.