A SINAPSE seed fund PhD studentship is available at the University of Dundee, in collaboration with the University of Edinburgh and industry partner Vascular Flow Technologies.
Arterial disease is responsible for up to one third of world deaths. Arterial surgery is performed on patients at risk of clinical events such as amputation, heart attack, stroke, or to create fistula for renal dialysis. The success of the treatment and the underlying arterial disease progression is adversely affected by abnormal blood flow, arterial wall stresses and stiffness and varies significantly between patients. Until recently there have been no means of assessing these key factors in clinical practice. Recent advances in ultrasound as a non-invasive imaging tool allows us to measure tissue stiffness, while advances in computational techniques allow is to model blood flow and the stresses on vessels. However these have not reached clinical practice
We will develop improved methods for identifying which patients will best benefit from surgery and which surgical procedures or devices are more likely to fail. We will use 3 recently available imaging-based methods for measuring the mechanical environment within arterial diseases.
We aim to test these new techniques in an important group of patients with leg arterial disease in order that we can validate the technique and assess its potential use in research and clinical practice. These patients are at risk of leg amputation. If we can select which patents would be most suitable for a particular surgical procedure and which medical device would have the greatest chance of success we will avoid un-necessary operations and improve the outcome for patients with leg arterial disease.
Application deadline: 1st May 2016
For more information on the project and how to apply, please visit: https://www.findaphd.com/search/ProjectDetails.aspx?PJID=73879
Details of the other awarded seed fund studentships to follow: PhD Opportunities.