N-(1-napthyl)-N’-(3-[I-123]-iodophenyl)-N-methylguanidine ([I-123]CNS 1261) is a novel SPET ligand developed for imaging the NMDA receptor intra-channel MK 801/PCP/ketamine site. Data was acquired in 7 healthy volunteers after bolus injection of [I-123]CNS …more

Objective: Lacunar stroke is common (25% of ischemic strokes) and mostly because of an intrinsic cerebral microvascular disease of unknown cause. Although considered primarily to be an ischemic process, the …more

Objective To determine the clinical effectiveness of laparoscopic and laparoscopically assisted surgery in comparison with open surgery for the treatment of colorectal cancer. Background Open resection is the standard method …more

Objective: Left ventricular hypertrophy (LVH) confers high cardiovascular risk. Regression of LVH reduces risk. Patients with blood pressure in the normal range and LVH are common. We investigated whether further …more

In this paper, we draw a link between cortical intrinsic curvature and the distributions of tangential connection lengths. We suggest that differential rates of surface expansion not only lead to …more

Functional magnetic resonance imaging (fMRI) in auditory experiments is a challenge, because the scanning procedure produces considerable noise that can interfere with the auditory paradigm. The noise might either mask …more

We employed event-related fMRI to investigate the neural correlates of source memory. Previous studies demonstrate that conscious (explicit) memory retrieval modulates a specific network of brain regions. Lateral and medial …more

Throughout our lives we acquire general knowledge about the world (semantic memory) while also retaining memories of specific events (episodic memory). Although these two forms of memory have been dissociated …more

Vagus nerve stimulation (VNS) has gained recognition as a treatment for refractory epilepsies where surgical treatment is not possible. While it appears that this treatment is effective in some patients, …more

Numerous reported burn injuries have been sustained during clinical AM procedures. The aim of this study was to investigate the possible factors that may be responsible for such burns. Experiments …more