Osteoporosis is highly prevalent in chronic obstructive pulmonary disease (COPD) patients and has been related to several clinical features. However, most studies have been in relatively small COPD cohorts. Therefore, …more
Two macaques (Macaca nemestrina) were trained to perform 3 self-directed behaviors on signal and to repeat behaviors after a ‘repeat’ signal. The cognitive processes underlying the monkeys’ repeat performance were …more
To evaluate the results of a recent change in practice in our institution using cutting balloon angioplasty instead of standard balloon angioplasty as the primary treatment for failing infra-inguinal vein …more
The paper documents a series of data integration workshops held in 2006 at the UK National e-Science Centre, summarizing a range of the problem/solution scenarios in multi-site and multi-scale data …more
Introduction: Tumor refractoriness to chemotherapy is frequently due to the acquisition of resistance. Resistant cells selected by exposure to chemotherapy agents may exhibit differences in [F-18]fluoro-2-deoxy-D-glucose (FDG) incorporation, as compared …more
Recent neuropsychological and neuroscientific research suggests that people who experience more deja vu display characteristic patterns in normal recognition memory. We conducted a large individual differences study (n = 206) …more
Long-term therapy with systemic corticosteroids is not recommended in the treatment of chronic obstructive pulmonary disease (COPD). However, experience demonstrates that some patients receive low dose therapy. Our objective was …more
BACKGROUND: The influence of white matter lesions on depressive symptoms in healthy ageing populations remains unclear. In this study, we examined the relationship between depressive symptoms and magnetic resonance imaging …more
The identification and quantification of morphological alterations that occur in the brain due to neurological disease, development and ageing, is of special interest in brain research. Design-based stereological methods have …more
Several studies have sought to test the neurodevelopmental hypothesis of schizophrenia through analysis of cortical gyrification. However, to date, results have been inconsistent. A possible reason for this is that …more
Background. The Cochrane Collaboration is an international organisation that aims to help people make well-informed decisions about healthcare by preparing, maintaining and promoting the accessibility of systematic reviews of the …more
Mangafodipir, a manganese-containing hepatobiliary contrast agent, is excreted in bile. We review the principles and practice of a contrast-enhanced MRC technique using mangafodipir and compare it with standard T2-weighted magnetic …more