Cerebral white matter hyperintensities (WMH) reflect accumulating white matter damage with aging and impair cognition. The role of childhood intelligence is rarely considered in associations between cognitive impairment and WMH. …more
A series of isotope labelling experiments was carried out to investigate the biosynthesis of fluoroacetate and 4-fluorothreonine in resting cells of Streptomyces cattleya. Previous studies have shown that fluoroacetaldehyde is …more
The conversion of littorine to hyoscyamine has been investigated by feeding deuterium labelled (RS)-[2-H-2]-, [3, 3-H-2(2)]-, [2, 3, 3-H-2(3)]- phenyllactic acids to transformed root cultures of Datura stramonium. Isolation and …more
Background and Purpose-Lower birth weight is associated with increased risk of stroke, but little is known about the mechanism for this association or influence in addition to vascular risk factors. …more
Background: The diagnosis of stroke or TIA in the emergency department is difficult, though important for early treatment. Circulating biomarkers might improve upon clinical assessment at admission. Methods: We recruited …more
Background and Purpose-The performance of validated prognostic clinical models in acute ischemic stroke might be improved by addition of data on blood biomarkers. Methods-We searched Medline and EMBASE from 1966 …more
Background: The cause of cerebral small vessel disease is not fully understood, yet it is important, accounting for about 25% of all strokes. It also increases the risk of having …more
Background: Blood oxygen level dependent (BOLD) T2* MRI detects signal variance within the myocardium based on changes in the deoxyhaemoglobin level following pharmacological stress, and it has the potential to …more
Background: The different levels of deoxyhemoglobin in the ischemic myocardium, induced by stressors such as dipyridamole, can be detected by blood oxygen level-dependent (BOLD) MRI and may be used to …more